Moracizina [INN-Spanish]
Brand names,
Moracizina [INN-Spanish]
Analogs
Moracizina [INN-Spanish]
Brand Names Mixture
Moracizina [INN-Spanish]
Chemical_Formula
C21H21N
Moracizina [INN-Spanish]
RX_link
http://www.rxlist.com/cgi/generic2/naft.htm
Moracizina [INN-Spanish]
fda sheet
Moracizina [INN-Spanish]
msds (material safety sheet)
Moracizina [INN-Spanish]
Synthesis Reference
No information avaliable
Moracizina [INN-Spanish]
Molecular Weight
287.398 g/mol
Moracizina [INN-Spanish]
Melting Point
No information avaliable
Moracizina [INN-Spanish]
H2O Solubility
No information avaliable
Moracizina [INN-Spanish]
State
Solid
Moracizina [INN-Spanish]
LogP
5.62
Moracizina [INN-Spanish]
Dosage Forms
Cream; Gel (1%)
Moracizina [INN-Spanish]
Indication
For the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Moracizina [INN-Spanish]
Pharmacology
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Naftifine has been shown to exhibit fungicidal activity in vitro against a broad spectrum of organisms including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Epidermophyton floccosum, and Microsporum canis, Microsporum audouini, and Microsporum gypseum; and fungistatic activity against Candida species including Candida albicans. However it is only used to treat the organisms listed in the indications.
Moracizina [INN-Spanish]
Absorption
Following single topical applications of 3H-labeled naftifine gel 1% to the skin of healthy subjects, up to 4.2% of the applied dose was absorbed.
Moracizina [INN-Spanish]
side effects and Toxicity
No information avaliable
Moracizina [INN-Spanish]
Patient Information
No information avaliable
Moracizina [INN-Spanish]
Organisms Affected
Yeast and other fungi